BDBM50369614 CHEMBL120787

SMILES: CC(C)(C)C(=O)Nc1cccc(SSc2cccc(NC(=O)C(C)(C)C)c2)c1

InChI Key: InChIKey=CUSUKFZFHVMKPZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50369614   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50369614 (CHEMBL120787) Show SMILES CC(C)(C)C(=O)Nc1cccc(SSc2cccc(NC(=O)C(C)(C)C)c2)c1 Show InChI InChI=1S/C22H28N2O2S2/c1-21(2,3)19(25)23-15-9-7-11-17(13-15)27-28-18-12-8-10-16(14-18)24-20(26)22(4,5)6/h7-14H,1-6H3,(H,23,25)(H,24,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem	PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Research Triangle Institute Curated by ChEMBL					Assay Description In vitro concentration required to inhibit 50% of cholesteryl ester transfer protein mediated cholesteryl ester transfer from HDL to VLDL and LDL in ...				J Med Chem 43: 3566-72 (2000) BindingDB Entry DOI: 10.7270/Q22J6CK6
					More data for this Ligand-Target Pair