BDBM50370773 CHEMBL219476

SMILES: Nc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c(N)c1

InChI Key: InChIKey=AOXYDDZYGQVAAT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50370773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50370773 (CHEMBL219476) Show SMILES Nc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c(N)c1 Show InChI InChI=1S/C20H17N3O2/c21-13-5-8-18(17(22)9-13)23-14-6-7-16-19(10-14)25-11-12-3-1-2-4-15(12)20(16)24/h1-10,23H,11,21-22H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eberhard-Karls-Universit£t Curated by ChEMBL					Assay Description Inhibition of p38 alpha				J Med Chem 49: 7912-5 (2006) Article DOI: 10.1021/jm061072p BindingDB Entry DOI: 10.7270/Q26Q1Z2K
					More data for this Ligand-Target Pair