BDBM50371104 CHEMBL243167

SMILES: COc1ccc(CCNC(=O)c2cccc3c2[nH]c2ccccc2c3=O)cc1OC

InChI Key: InChIKey=UZSASCBZXRCVQS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50371104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family G member 2 (Homo sapiens (Human))	BDBM50371104 (CHEMBL243167) Show SMILES COc1ccc(CCNC(=O)c2cccc3c2[nH]c2ccccc2c3=O)cc1OC Show InChI InChI=1S/C24H22N2O4/c1-29-20-11-10-15(14-21(20)30-2)12-13-25-24(28)18-8-5-7-17-22(18)26-19-9-4-3-6-16(19)23(17)27/h3-11,14H,12-13H2,1-2H3,(H,25,28)(H,26,27)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5063 CNRS/Universit£ Joseph Fourier-Grenoble I Curated by ChEMBL					Assay Description Inhibition of ABCG2 expressed in HEK293 cells assessed as mitoxantrone-mediated efflux by flow cytometry				Bioorg Med Chem 15: 2892-7 (2007) Article DOI: 10.1016/j.bmc.2007.02.017 BindingDB Entry DOI: 10.7270/Q2N58N6T
					More data for this Ligand-Target Pair