Found 4 hits for monomerid = 50372219 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50372219
(CHEMBL257007)Show InChI InChI=1S/C21H24ClN3/c1-24(16-19-13-20(22)8-7-18(19)14-23)21-9-11-25(12-10-21)15-17-5-3-2-4-6-17/h2-8,13,21H,9-12,15-16H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 270 | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Inhibition of human iNOS expressed in human DLD1 cells after 1 hr |
Bioorg Med Chem Lett 18: 336-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, inducible
(Homo sapiens (Human)) | BDBM50372219
(CHEMBL257007)Show InChI InChI=1S/C21H24ClN3/c1-24(16-19-13-20(22)8-7-18(19)14-23)21-9-11-25(12-10-21)15-17-5-3-2-4-6-17/h2-8,13,21H,9-12,15-16H2,1H3 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Inhibition of cytokine-induced iNOS activity in human DLD1 cells after 24 hrs |
Bioorg Med Chem Lett 18: 336-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, brain
(Homo sapiens (Human)) | BDBM50372219
(CHEMBL257007)Show InChI InChI=1S/C21H24ClN3/c1-24(16-19-13-20(22)8-7-18(19)14-23)21-9-11-25(12-10-21)15-17-5-3-2-4-6-17/h2-8,13,21H,9-12,15-16H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Inhibition of human nNOS expressed in insect SF9 cells after 1 hr |
Bioorg Med Chem Lett 18: 336-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q |
More data for this Ligand-Target Pair | |
Nitric oxide synthase, endothelial
(Homo sapiens (Human)) | BDBM50372219
(CHEMBL257007)Show InChI InChI=1S/C21H24ClN3/c1-24(16-19-13-20(22)8-7-18(19)14-23)21-9-11-25(12-10-21)15-17-5-3-2-4-6-17/h2-8,13,21H,9-12,15-16H2,1H3 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Adolor Corporation
Curated by ChEMBL
| Assay Description Inhibition of human eNOS expressed in insect SF9 cells after 1 hr |
Bioorg Med Chem Lett 18: 336-43 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.073 BindingDB Entry DOI: 10.7270/Q2H9961Q |
More data for this Ligand-Target Pair | |