BDBM50372530 CHEMBL271366

SMILES: CCOC(=O)CN(C1CCN(CC1)c1ccncc1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=PNXHHBOOJOYZML-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50372530 (CHEMBL271366) Show SMILES CCOC(=O)CN(C1CCN(CC1)c1ccncc1)C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C27H30ClN3O5S/c1-2-36-27(33)19-31(24-9-14-30(15-10-24)23-7-12-29-13-8-23)26(32)11-16-37(34,35)25-6-4-20-17-22(28)5-3-21(20)18-25/h3-8,12-13,17-18,24H,2,9-11,14-16,19H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 16: 2243-60 (2008) Article DOI: 10.1016/j.bmc.2007.11.073 BindingDB Entry DOI: 10.7270/Q2ZC83QS
					More data for this Ligand-Target Pair