BDBM50372543 CHEMBL407407

SMILES: NOC(=O)CN(CCCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)C1CCN(CC1)c1ccncc1

InChI Key: InChIKey=RWSFKSXINPCVFT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372543   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50372543 (CHEMBL407407) Show SMILES NOC(=O)CN(CCCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)C1CCN(CC1)c1ccncc1 Show InChI InChI=1S/C26H29ClN4O5S/c27-22-4-2-21-17-24(5-3-20(21)16-22)37(34,35)15-1-12-31(18-25(32)36-28)26(33)19-8-13-30(14-9-19)23-6-10-29-11-7-23/h2-7,10-11,16-17,19H,1,8-9,12-15,18,28H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 16: 2243-60 (2008) Article DOI: 10.1016/j.bmc.2007.11.073 BindingDB Entry DOI: 10.7270/Q2ZC83QS
					More data for this Ligand-Target Pair