BDBM50372549 CHEMBL270941

SMILES: CN(C1CCN(CC1)c1ccncc1)C(=O)CCCS(=O)(=O)c1ccc2cc(Cl)ccc2c1

InChI Key: InChIKey=PBHIXPUHPSKDPM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50372549 (CHEMBL270941) Show SMILES CN(C1CCN(CC1)c1ccncc1)C(=O)CCCS(=O)(=O)c1ccc2cc(Cl)ccc2c1 Show InChI InChI=1S/C25H28ClN3O3S/c1-28(22-10-14-29(15-11-22)23-8-12-27-13-9-23)25(30)3-2-16-33(31,32)24-7-5-19-17-21(26)6-4-20(19)18-24/h4-9,12-13,17-18,22H,2-3,10-11,14-16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of human factor 10a				Bioorg Med Chem 16: 2243-60 (2008) Article DOI: 10.1016/j.bmc.2007.11.073 BindingDB Entry DOI: 10.7270/Q2ZC83QS
					More data for this Ligand-Target Pair