BDBM50372904 CHEMBL404723

SMILES: CCOc1ccc(C=C2SC(=S)NC2=O)cc1OC1CCCC1

InChI Key: InChIKey=HBPYGOFQTUMLGW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50372904   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50372904 (CHEMBL404723) Show SMILES CCOc1ccc(C=C2SC(=S)NC2=O)cc1OC1CCCC1 |w:7.6| Show InChI InChI=1S/C17H19NO3S2/c1-2-20-13-8-7-11(10-15-16(19)18-17(22)23-15)9-14(13)21-12-5-3-4-6-12/h7-10,12H,2-6H2,1H3,(H,18,19,22)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Paisley Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 18: 2032-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.117 BindingDB Entry DOI: 10.7270/Q2BG2PVS
					More data for this Ligand-Target Pair
Phosphodiesterase 3 (PDE3) (Homo sapiens (Human))	BDBM50372904 (CHEMBL404723) Show SMILES CCOc1ccc(C=C2SC(=S)NC2=O)cc1OC1CCCC1 |w:7.6| Show InChI InChI=1S/C17H19NO3S2/c1-2-20-13-8-7-11(10-15-16(19)18-17(22)23-15)9-14(13)21-12-5-3-4-6-12/h7-10,12H,2-6H2,1H3,(H,18,19,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Paisley Curated by ChEMBL					Assay Description Inhibition of PDE3A				Bioorg Med Chem Lett 18: 2032-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.117 BindingDB Entry DOI: 10.7270/Q2BG2PVS
					More data for this Ligand-Target Pair