BDBM50372912 CHEMBL429680

SMILES: COc1ccc(\C=C2/SC(=S)N(CC=C)C2=O)cc1OC1CCCC1

InChI Key: InChIKey=BLKBSWZKFSRGMD-ATVHPVEESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50372912   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50372912 (CHEMBL429680) Show SMILES COc1ccc(\C=C2/SC(=S)N(CC=C)C2=O)cc1OC1CCCC1 Show InChI InChI=1S/C19H21NO3S2/c1-3-10-20-18(21)17(25-19(20)24)12-13-8-9-15(22-2)16(11-13)23-14-6-4-5-7-14/h3,8-9,11-12,14H,1,4-7,10H2,2H3/b17-12-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Paisley Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 18: 2032-7 (2008) Article DOI: 10.1016/j.bmcl.2008.01.117 BindingDB Entry DOI: 10.7270/Q2BG2PVS
					More data for this Ligand-Target Pair