null

SMILES: Cc1cc(=O)[nH]c2ccc-3c(COc4cccc(CO)c-34)c12

InChI Key: InChIKey=HNYRSZRBOVPOHQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50373232   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50373232 (CHEMBL257151) Show SMILES Cc1cc(=O)[nH]c2ccc-3c(COc4cccc(CO)c-34)c12 Show InChI InChI=1S/C18H15NO3/c1-10-7-16(21)19-14-6-5-12-13(17(10)14)9-22-15-4-2-3-11(8-20)18(12)15/h2-7,20H,8-9H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assay				Bioorg Med Chem Lett 18: 3431-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50373232 (CHEMBL257151) Show SMILES Cc1cc(=O)[nH]c2ccc-3c(COc4cccc(CO)c-34)c12 Show InChI InChI=1S/C18H15NO3/c1-10-7-16(21)19-14-6-5-12-13(17(10)14)9-22-15-4-2-3-11(8-20)18(12)15/h2-7,20H,8-9H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Activity at androgen receptor in human Saos2 cells assessed as IL6 repression				Bioorg Med Chem Lett 18: 3431-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50373232 (CHEMBL257151) Show SMILES Cc1cc(=O)[nH]c2ccc-3c(COc4cccc(CO)c-34)c12 Show InChI InChI=1S/C18H15NO3/c1-10-7-16(21)19-14-6-5-12-13(17(10)14)9-22-15-4-2-3-11(8-20)18(12)15/h2-7,20H,8-9H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assay				Bioorg Med Chem Lett 18: 3431-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50373232 (CHEMBL257151) Show SMILES Cc1cc(=O)[nH]c2ccc-3c(COc4cccc(CO)c-34)c12 Show InChI InChI=1S/C18H15NO3/c1-10-7-16(21)19-14-6-5-12-13(17(10)14)9-22-15-4-2-3-11(8-20)18(12)15/h2-7,20H,8-9H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assay				Bioorg Med Chem Lett 18: 3431-5 (2008) Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9
					More data for this Ligand-Target Pair