Found 4 hits for monomerid = 50373241 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Androgen receptor
(Homo sapiens (Human)) | BDBM50373241
(CHEMBL402136)Show SMILES COc1cccc2COc3c(ccc4[nH]c(=O)cc(c34)C(F)(F)F)-c12 Show InChI InChI=1S/C18H12F3NO3/c1-24-13-4-2-3-9-8-25-17-10(15(9)13)5-6-12-16(17)11(18(19,20)21)7-14(23)22-12/h2-7H,8H2,1H3,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Binding affinity to human androgen receptor expressed in monkey COS7 cells by whole cell binding assay |
Bioorg Med Chem Lett 18: 3431-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50373241
(CHEMBL402136)Show SMILES COc1cccc2COc3c(ccc4[nH]c(=O)cc(c34)C(F)(F)F)-c12 Show InChI InChI=1S/C18H12F3NO3/c1-24-13-4-2-3-9-8-25-17-10(15(9)13)5-6-12-16(17)11(18(19,20)21)7-14(23)22-12/h2-7H,8H2,1H3,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Antagonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assay |
Bioorg Med Chem Lett 18: 3431-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50373241
(CHEMBL402136)Show SMILES COc1cccc2COc3c(ccc4[nH]c(=O)cc(c34)C(F)(F)F)-c12 Show InChI InChI=1S/C18H12F3NO3/c1-24-13-4-2-3-9-8-25-17-10(15(9)13)5-6-12-16(17)11(18(19,20)21)7-14(23)22-12/h2-7H,8H2,1H3,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 477 | n/a | n/a | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Activity at androgen receptor in human Saos2 cells assessed as IL6 repression |
Bioorg Med Chem Lett 18: 3431-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9 |
More data for this Ligand-Target Pair | |
Androgen receptor
(Homo sapiens (Human)) | BDBM50373241
(CHEMBL402136)Show SMILES COc1cccc2COc3c(ccc4[nH]c(=O)cc(c34)C(F)(F)F)-c12 Show InChI InChI=1S/C18H12F3NO3/c1-24-13-4-2-3-9-8-25-17-10(15(9)13)5-6-12-16(17)11(18(19,20)21)7-14(23)22-12/h2-7H,8H2,1H3,(H,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Ligand Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human androgen receptor african green monkey CV1 cells by cotransfection assay |
Bioorg Med Chem Lett 18: 3431-5 (2008)
Article DOI: 10.1016/j.bmcl.2008.03.085 BindingDB Entry DOI: 10.7270/Q25M66J9 |
More data for this Ligand-Target Pair | |