BDBM50373489 CHEMBL407818

SMILES: Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1

InChI Key: InChIKey=GDEQPGACTRNZFK-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50373489   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50373489 (CHEMBL407818) Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from cloned human dopamine D3 receptor expressed in CHO cells				J Med Chem 51: 1800-10 (2008) Article DOI: 10.1021/jm701375u BindingDB Entry DOI: 10.7270/Q2RB75FF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50373489 (CHEMBL407818) Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from cloned human dopamine D2L receptor expressed in CHO cells				J Med Chem 51: 1800-10 (2008) Article DOI: 10.1021/jm701375u BindingDB Entry DOI: 10.7270/Q2RB75FF
					More data for this Ligand-Target Pair
Dopamine D1 receptor (Sus scrofa)	BDBM50373489 (CHEMBL407818) Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23990 from dopamine D1 receptor in pig striatal membrane				J Med Chem 51: 1800-10 (2008) Article DOI: 10.1021/jm701375u BindingDB Entry DOI: 10.7270/Q2RB75FF
					More data for this Ligand-Target Pair
5-HT2 (PIG)	BDBM50373489 (CHEMBL407818) Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2 receptor in pig cortical membranes				J Med Chem 51: 1800-10 (2008) Article DOI: 10.1021/jm701375u BindingDB Entry DOI: 10.7270/Q2RB75FF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50373489 (CHEMBL407818) Show SMILES Oc1ccc(cc1)N1CCN(Cc2cnn3ccccc23)CC1 Show InChI InChI=1S/C18H20N4O/c23-17-6-4-16(5-7-17)21-11-9-20(10-12-21)14-15-13-19-22-8-2-1-3-18(15)22/h1-8,13,23H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from cloned human dopamine D2S receptor expressed in CHO cells				J Med Chem 51: 1800-10 (2008) Article DOI: 10.1021/jm701375u BindingDB Entry DOI: 10.7270/Q2RB75FF
					More data for this Ligand-Target Pair