Found 4 hits for monomerid = 50373538 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373538
(CHEMBL273118)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(NCc2cc3ccccc3s2)cc(n1)C(F)(F)F Show InChI InChI=1S/C21H16F3N3O2S2/c1-31(28,29)16-8-6-13(7-9-16)20-26-18(21(22,23)24)11-19(27-20)25-12-15-10-14-4-2-3-5-17(14)30-15/h2-11H,12H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 293 | n/a | n/a | n/a | n/a | n/a | n/a |
Faes Farma S.A.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 in human whole blood |
Bioorg Med Chem 16: 2183-99 (2008)
Article DOI: 10.1016/j.bmc.2007.11.079
BindingDB Entry DOI: 10.7270/Q2GX4CDQ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373538
(CHEMBL273118)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(NCc2cc3ccccc3s2)cc(n1)C(F)(F)F Show InChI InChI=1S/C21H16F3N3O2S2/c1-31(28,29)16-8-6-13(7-9-16)20-26-18(21(22,23)24)11-19(27-20)25-12-15-10-14-4-2-3-5-17(14)30-15/h2-11H,12H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 293 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8
BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373538
(CHEMBL273118)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(NCc2cc3ccccc3s2)cc(n1)C(F)(F)F Show InChI InChI=1S/C21H16F3N3O2S2/c1-31(28,29)16-8-6-13(7-9-16)20-26-18(21(22,23)24)11-19(27-20)25-12-15-10-14-4-2-3-5-17(14)30-15/h2-11H,12H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 3.41E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8
BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373538
(CHEMBL273118)Show SMILES CS(=O)(=O)c1ccc(cc1)-c1nc(NCc2cc3ccccc3s2)cc(n1)C(F)(F)F Show InChI InChI=1S/C21H16F3N3O2S2/c1-31(28,29)16-8-6-13(7-9-16)20-26-18(21(22,23)24)11-19(27-20)25-12-15-10-14-4-2-3-5-17(14)30-15/h2-11H,12H2,1H3,(H,25,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.92 | n/a | n/a | n/a | n/a | n/a | n/a |
Faes Farma S.A.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 |
Bioorg Med Chem 16: 2183-99 (2008)
Article DOI: 10.1016/j.bmc.2007.11.079
BindingDB Entry DOI: 10.7270/Q2GX4CDQ |
More data for this
Ligand-Target Pair | |
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