Found 3 hits for monomerid = 50373575 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373575
(CHEMBL270517)Show SMILES CCc1c(NCc2cccs2)nc(nc1C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H18F3N3O2S2/c1-3-15-16(19(20,21)22)24-17(12-6-8-14(9-7-12)29(2,26)27)25-18(15)23-11-13-5-4-10-28-13/h4-10H,3,11H2,1-2H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Faes Farma S.A.
Curated by ChEMBL
| Assay Description
Inhibition of human COX2 in human whole blood |
Bioorg Med Chem 16: 2183-99 (2008)
Article DOI: 10.1016/j.bmc.2007.11.079
BindingDB Entry DOI: 10.7270/Q2GX4CDQ |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373575
(CHEMBL270517)Show SMILES CCc1c(NCc2cccs2)nc(nc1C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H18F3N3O2S2/c1-3-15-16(19(20,21)22)24-17(12-6-8-14(9-7-12)29(2,26)27)25-18(15)23-11-13-5-4-10-28-13/h4-10H,3,11H2,1-2H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8
BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this
Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373575
(CHEMBL270517)Show SMILES CCc1c(NCc2cccs2)nc(nc1C(F)(F)F)-c1ccc(cc1)S(C)(=O)=O Show InChI InChI=1S/C19H18F3N3O2S2/c1-3-15-16(19(20,21)22)24-17(12-6-8-14(9-7-12)29(2,26)27)25-18(15)23-11-13-5-4-10-28-13/h4-10H,3,11H2,1-2H3,(H,23,24,25) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
| n/a | n/a | 8.27E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8
BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this
Ligand-Target Pair | |
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