Found 3 hits for monomerid = 50373595 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373595
(CHEMBL269818)Show SMILES Cc1ccc(CNc2cc(nc(n2)-c2ccc(cc2)S(C)(=O)=O)C(F)(F)F)s1 Show InChI InChI=1S/C18H16F3N3O2S2/c1-11-3-6-13(27-11)10-22-16-9-15(18(19,20)21)23-17(24-16)12-4-7-14(8-5-12)28(2,25)26/h3-9H,10H2,1-2H3,(H,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 11.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Faes Farma S.A.
Curated by ChEMBL
| Assay Description Inhibition of human COX2 in human whole blood |
Bioorg Med Chem 16: 2183-99 (2008)
Article DOI: 10.1016/j.bmc.2007.11.079 BindingDB Entry DOI: 10.7270/Q2GX4CDQ |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373595
(CHEMBL269818)Show SMILES Cc1ccc(CNc2cc(nc(n2)-c2ccc(cc2)S(C)(=O)=O)C(F)(F)F)s1 Show InChI InChI=1S/C18H16F3N3O2S2/c1-11-3-6-13(27-11)10-22-16-9-15(18(19,20)21)23-17(24-16)12-4-7-14(8-5-12)28(2,25)26/h3-9H,10H2,1-2H3,(H,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 8.55E+7 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8 BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this Ligand-Target Pair | |
Prostaglandin G/H synthase 2
(Homo sapiens (Human)) | BDBM50373595
(CHEMBL269818)Show SMILES Cc1ccc(CNc2cc(nc(n2)-c2ccc(cc2)S(C)(=O)=O)C(F)(F)F)s1 Show InChI InChI=1S/C18H16F3N3O2S2/c1-11-3-6-13(27-11)10-22-16-9-15(18(19,20)21)23-17(24-16)12-4-7-14(8-5-12)28(2,25)26/h3-9H,10H2,1-2H3,(H,22,23,24) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of COX2 in Homo sapiens (human) whole blood |
Citation and Details
Article DOI: 10.1007/s00044-011-9566-8 BindingDB Entry DOI: 10.7270/Q2Q81GZM |
More data for this Ligand-Target Pair | |