null

SMILES: OC1(CCN(CCCNS(=O)(=O)c2ccccc2)CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=VHKQMVRYKPZJFI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374804   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374804 (CHEMBL270631) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H25ClN2O3S/c21-18-9-7-17(8-10-18)20(24)11-15-23(16-12-20)14-4-13-22-27(25,26)19-5-2-1-3-6-19/h1-3,5-10,22,24H,4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374804 (CHEMBL270631) Show SMILES OC1(CCN(CCCNS(=O)(=O)c2ccccc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C20H25ClN2O3S/c21-18-9-7-17(8-10-18)20(24)11-15-23(16-12-20)14-4-13-22-27(25,26)19-5-2-1-3-6-19/h1-3,5-10,22,24H,4,11-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair