BDBM50374816 CHEMBL256404

SMILES: Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1

InChI Key: InChIKey=ZGHLZIJPMKXIHH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374816   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374816 (CHEMBL256404) Show SMILES Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H27ClN2O3S/c1-17-5-2-3-6-20(17)28(26,27)23-13-4-14-24-15-11-21(25,12-16-24)18-7-9-19(22)10-8-18/h2-3,5-10,23,25H,4,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374816 (CHEMBL256404) Show SMILES Cc1ccccc1S(=O)(=O)NCCCN1CCC(O)(CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H27ClN2O3S/c1-17-5-2-3-6-20(17)28(26,27)23-13-4-14-24-15-11-21(25,12-16-24)18-7-9-19(22)10-8-18/h2-3,5-10,23,25H,4,11-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair