BDBM50374838 CHEMBL256887

SMILES: OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1c(F)cc(F)cc1Br)c1ccc(Cl)cc1

InChI Key: InChIKey=WXRNCZLBVFFDCH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374838 (CHEMBL256887) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1c(F)cc(F)cc1Br)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24BrClF2N2O3S/c23-19-13-17(25)14-20(26)21(19)32(30,31)28-9-5-18(6-10-28)27-11-7-22(29,8-12-27)15-1-3-16(24)4-2-15/h1-4,13-14,18,29H,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human CCR1 receptor expressed in THP1 cells assessed as human MIP-1-alpha-stimulated intracellular calcium level by FLIPR assa...				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50374838 (CHEMBL256887) Show SMILES OC1(CCN(CC1)C1CCN(CC1)S(=O)(=O)c1c(F)cc(F)cc1Br)c1ccc(Cl)cc1 Show InChI InChI=1S/C22H24BrClF2N2O3S/c23-19-13-17(25)14-20(26)21(19)32(30,31)28-9-5-18(6-10-28)27-11-7-22(29,8-12-27)15-1-3-16(24)4-2-15/h1-4,13-14,18,29H,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]MIP1-alpha from human CCR1 receptor expressed in THP1 cells				Bioorg Med Chem Lett 18: 2215-21 (2008) Article DOI: 10.1016/j.bmcl.2007.09.068 BindingDB Entry DOI: 10.7270/Q21C1XQP
					More data for this Ligand-Target Pair