BDBM50375210 CHEMBL406909

SMILES: CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(C)=O

InChI Key: InChIKey=HVFKDVGFDPVRIU-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50375210 (CHEMBL406909) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(C)=O Show InChI InChI=1S/C24H22N4O2/c1-4-28-19-8-5-13(12(2)29)9-15(19)21-16-10-25-24(30)22(16)20-14(23(21)28)6-7-18-17(20)11-27(3)26-18/h5,8-9,11H,4,6-7,10H2,1-3H3,(H,25,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of VEGFR2				Bioorg Med Chem Lett 18: 2368-72 (2008) Article DOI: 10.1016/j.bmcl.2008.02.069 BindingDB Entry DOI: 10.7270/Q2ZG6T3P
					More data for this Ligand-Target Pair
Angiopoietin-1 receptor (Homo sapiens (Human))	BDBM50375210 (CHEMBL406909) Show SMILES CCn1c2ccc(cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12)C(C)=O Show InChI InChI=1S/C24H22N4O2/c1-4-28-19-8-5-13(12(2)29)9-15(19)21-16-10-25-24(30)22(16)20-14(23(21)28)6-7-18-17(20)11-27(3)26-18/h5,8-9,11H,4,6-7,10H2,1-3H3,(H,25,30)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Inhibition of TIE2				Bioorg Med Chem Lett 18: 2368-72 (2008) Article DOI: 10.1016/j.bmcl.2008.02.069 BindingDB Entry DOI: 10.7270/Q2ZG6T3P
					More data for this Ligand-Target Pair