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BDBM50375357 CHEMBL412139

SMILES: COc1cc(Nc2nn3c(NC[C@H](C)N)cc(C)nc3c2C(N)=O)cc(OC)c1

InChI Key: InChIKey=JHEUXHLNVYZLBG-JTQLQIEISA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375357   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM50375357
PNG
(CHEMBL412139)
Show SMILES COc1cc(Nc2nn3c(NC[C@H](C)N)cc(C)nc3c2C(N)=O)cc(OC)c1
Show InChI InChI=1S/C19H25N7O3/c1-10(20)9-22-15-5-11(2)23-19-16(17(21)27)18(25-26(15)19)24-12-6-13(28-3)8-14(7-12)29-4/h5-8,10,22H,9,20H2,1-4H3,(H2,21,27)(H,24,25)/t10-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.99E+3n/an/an/an/an/an/a



Kissei Pharmaceutical Company Ltd

Curated by ChEMBL


Assay Description
Inhibition of human cSrc


Bioorg Med Chem 16: 909-21 (2008)


Article DOI: 10.1016/j.bmc.2007.10.068
BindingDB Entry DOI: 10.7270/Q2CF9R01
More data for this
Ligand-Target Pair