BDBM50375426 CHEMBL268788

SMILES: C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnc2ccccc2c1

InChI Key: InChIKey=HMLOAJPEEJRYFG-YWIPDPJESA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50375426   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375426 (CHEMBL268788) Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnc2ccccc2c1 |c:14,t:7| Show InChI InChI=1S/C38H39NO2/c1-22-17-33-31-15-13-26-19-29(40)14-16-30(26)35(31)32(20-38(33,2)36(22)37(41)25-11-12-25)24-9-7-23(8-10-24)28-18-27-5-3-4-6-34(27)39-21-28/h3-10,18-19,21-22,25,31-33,36H,11-17,20H2,1-2H3/t22-,31+,32-,33+,36-,38+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.14	n/a	n/a	n/a	n/a	n/a	n/a
NV Organon Curated by ChEMBL					Assay Description Antagonist activity at human PRB expressed in CHO cells assessed as inhibition of Org 2058 induced-transactivation				Bioorg Med Chem 16: 2753-63 (2008) Article DOI: 10.1016/j.bmc.2008.01.010 BindingDB Entry DOI: 10.7270/Q2Z89D9G
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50375426 (CHEMBL268788) Show SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]2(C)[C@H]1C(=O)C1CC1)c1ccc(cc1)-c1cnc2ccccc2c1 |c:14,t:7| Show InChI InChI=1S/C38H39NO2/c1-22-17-33-31-15-13-26-19-29(40)14-16-30(26)35(31)32(20-38(33,2)36(22)37(41)25-11-12-25)24-9-7-23(8-10-24)28-18-27-5-3-4-6-34(27)39-21-28/h3-10,18-19,21-22,25,31-33,36H,11-17,20H2,1-2H3/t22-,31+,32-,33+,36-,38+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
NV Organon Curated by ChEMBL					Assay Description Agonist activity at human PRB expressed in CHO cells				Bioorg Med Chem 16: 2753-63 (2008) Article DOI: 10.1016/j.bmc.2008.01.010 BindingDB Entry DOI: 10.7270/Q2Z89D9G
					More data for this Ligand-Target Pair