BDBM50375714 CHEMBL262357

SMILES: CNCc1cnc(C)cc1Oc1ccccc1OC

InChI Key: InChIKey=LAMKUIMKGNOGQJ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50375714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50375714 (CHEMBL262357) Show SMILES CNCc1cnc(C)cc1Oc1ccccc1OC Show InChI InChI=1S/C15H18N2O2/c1-11-8-15(12(9-16-2)10-17-11)19-14-7-5-4-6-13(14)18-3/h4-8,10,16H,9H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]Citalopram uptake in human 5HTT transfected HEK293 cells				Bioorg Med Chem Lett 18: 1795-8 (2008) Article DOI: 10.1016/j.bmcl.2008.02.036 BindingDB Entry DOI: 10.7270/Q2125TH5
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50375714 (CHEMBL262357) Show SMILES CNCc1cnc(C)cc1Oc1ccccc1OC Show InChI InChI=1S/C15H18N2O2/c1-11-8-15(12(9-16-2)10-17-11)19-14-7-5-4-6-13(14)18-3/h4-8,10,16H,9H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	921	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]Nisoxetine uptake in human noradrenaline transporter transfected HEK293 cells				Bioorg Med Chem Lett 18: 1795-8 (2008) Article DOI: 10.1016/j.bmcl.2008.02.036 BindingDB Entry DOI: 10.7270/Q2125TH5
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50375714 (CHEMBL262357) Show SMILES CNCc1cnc(C)cc1Oc1ccccc1OC Show InChI InChI=1S/C15H18N2O2/c1-11-8-15(12(9-16-2)10-17-11)19-14-7-5-4-6-13(14)18-3/h4-8,10,16H,9H2,1-3H3	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of [3H]WIN-35428 uptake in human DAT transfected HEK293 cells				Bioorg Med Chem Lett 18: 1795-8 (2008) Article DOI: 10.1016/j.bmcl.2008.02.036 BindingDB Entry DOI: 10.7270/Q2125TH5
					More data for this Ligand-Target Pair