BDBM50375838 CHEMBL271835

SMILES: Cn1c(ccc1-c1cc2c(N(Cc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N

InChI Key: InChIKey=FPYZTDDUPXWEQH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50375838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50375838 (CHEMBL271835) Show SMILES Cn1c(ccc1-c1cc2c(N(Cc3ccccc3)C(=O)C2(C)C)c(F)c1)C#N Show InChI InChI=1S/C23H20FN3O/c1-23(2)18-11-16(20-10-9-17(13-25)26(20)3)12-19(24)21(18)27(22(23)28)14-15-7-5-4-6-8-15/h4-12H,14H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	164	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Antagonist activity at human PR expressed in human T47D cells assessed as inhibition of progesterone induced alkaline phosphatase				J Med Chem 51: 1861-73 (2008) Article DOI: 10.1021/jm701080t BindingDB Entry DOI: 10.7270/Q2G44R56
					More data for this Ligand-Target Pair