BDBM50376097 CHEMBL258700

SMILES: COc1ccc2[nH]c-3c(CC(=O)Nc4cccnc-34)c2c1

InChI Key: InChIKey=OABFHHUXJBWVRL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376097   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50376097 (CHEMBL258700) Show SMILES COc1ccc2[nH]c-3c(CC(=O)Nc4cccnc-34)c2c1 Show InChI InChI=1S/C16H13N3O2/c1-21-9-4-5-12-10(7-9)11-8-14(20)18-13-3-2-6-17-16(13)15(11)19-12/h2-7,19H,8H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of recombinant CDK5/p25 expressed in Escherichia coli				J Med Chem 51: 2196-207 (2008) Article DOI: 10.1021/jm701582f BindingDB Entry DOI: 10.7270/Q2SF2X22
					More data for this Ligand-Target Pair