BDBM50376106 CHEMBL259638

SMILES: O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2ncccc2N1

InChI Key: InChIKey=MGQSIUXWCFOENX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50376106 (CHEMBL259638) Show SMILES O=C1Cc2c([nH]c3ccc(cc23)C#N)-c2ncccc2N1 Show InChI InChI=1S/C16H10N4O/c17-8-9-3-4-12-10(6-9)11-7-14(21)19-13-2-1-5-18-16(13)15(11)20-12/h1-6,20H,7H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Technische Universit£t Braunschweig Curated by ChEMBL					Assay Description Inhibition of recombinant CDK5/p25 expressed in Escherichia coli				J Med Chem 51: 2196-207 (2008) Article DOI: 10.1021/jm701582f BindingDB Entry DOI: 10.7270/Q2SF2X22
					More data for this Ligand-Target Pair