BDBM50376170 CHEMBL265446

SMILES: O=C1NCc2c1c1C(=O)NC(=O)c1c1c2[nH]c2ccccc12

InChI Key: InChIKey=JHXIUVYOWSHFDL-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376170   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase Chk1 (Homo sapiens (Human))	BDBM50376170 (CHEMBL265446) Show SMILES O=C1NCc2c1c1C(=O)NC(=O)c1c1c2[nH]c2ccccc12 Show InChI InChI=1S/C16H9N3O3/c20-14-10-7(5-17-14)13-9(6-3-1-2-4-8(6)18-13)11-12(10)16(22)19-15(11)21/h1-4,18H,5H2,(H,17,20)(H,19,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Blaise Pascal Curated by ChEMBL					Assay Description Inhibition of human Chk1				Bioorg Med Chem 16: 4419-30 (2008) Article DOI: 10.1016/j.bmc.2008.02.061 BindingDB Entry DOI: 10.7270/Q24Q7VV9
					More data for this Ligand-Target Pair