BDBM50376228 CHEMBL261021

SMILES: CNC(=O)c1ccc(C)c(Nc2nc(N)nc3n(ncc23)-c2ccccc2)c1

InChI Key: InChIKey=FCRBCMOVJUGGHZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50376228 (CHEMBL261021) Show SMILES CNC(=O)c1ccc(C)c(Nc2nc(N)nc3n(ncc23)-c2ccccc2)c1 Show InChI InChI=1S/C20H19N7O/c1-12-8-9-13(19(28)22-2)10-16(12)24-17-15-11-23-27(14-6-4-3-5-7-14)18(15)26-20(21)25-17/h3-11H,1-2H3,(H,22,28)(H3,21,24,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylation				Bioorg Med Chem Lett 18: 2652-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.019 BindingDB Entry DOI: 10.7270/Q2C53MR6
					More data for this Ligand-Target Pair