BDBM50376231 CHEMBL410667

SMILES: CCCCNC(=O)c1ccc(C)c(Nc2ncnc3n(ncc23)-c2ccccc2)c1

InChI Key: InChIKey=JLJRXOZNFCRZST-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50376231 (CHEMBL410667) Show SMILES CCCCNC(=O)c1ccc(C)c(Nc2ncnc3n(ncc23)-c2ccccc2)c1 Show InChI InChI=1S/C23H24N6O/c1-3-4-12-24-23(30)17-11-10-16(2)20(13-17)28-21-19-14-27-29(22(19)26-15-25-21)18-8-6-5-7-9-18/h5-11,13-15H,3-4,12H2,1-2H3,(H,24,30)(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylation				Bioorg Med Chem Lett 18: 2652-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.019 BindingDB Entry DOI: 10.7270/Q2C53MR6
					More data for this Ligand-Target Pair