BDBM50376235 CHEMBL439267

SMILES: Cc1ccc(cc1Nc1ncnc2n(ncc12)-c1ccccc1)C(N)=O

InChI Key: InChIKey=OWKREXHHHNVPNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50376235 (CHEMBL439267) Show SMILES Cc1ccc(cc1Nc1ncnc2n(ncc12)-c1ccccc1)C(N)=O Show InChI InChI=1S/C19H16N6O/c1-12-7-8-13(17(20)26)9-16(12)24-18-15-10-23-25(19(15)22-11-21-18)14-5-3-2-4-6-14/h2-11H,1H3,(H2,20,26)(H,21,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylation				Bioorg Med Chem Lett 18: 2652-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.019 BindingDB Entry DOI: 10.7270/Q2C53MR6
					More data for this Ligand-Target Pair