BDBM50376246 CHEMBL409916

SMILES: CNC(=O)c1ccc(C)c(Nc2nc(NCCN3CCCC3)nc3n(ncc23)-c2ccccc2)c1

InChI Key: InChIKey=LKYUBYFPTUNPFJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50376246 (CHEMBL409916) Show SMILES CNC(=O)c1ccc(C)c(Nc2nc(NCCN3CCCC3)nc3n(ncc23)-c2ccccc2)c1 Show InChI InChI=1S/C26H30N8O/c1-18-10-11-19(25(35)27-2)16-22(18)30-23-21-17-29-34(20-8-4-3-5-9-20)24(21)32-26(31-23)28-12-15-33-13-6-7-14-33/h3-5,8-11,16-17H,6-7,12-15H2,1-2H3,(H,27,35)(H2,28,30,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of human recombinant p38alpha-mediated myelin basic protein phosphorylation				Bioorg Med Chem Lett 18: 2652-7 (2008) Article DOI: 10.1016/j.bmcl.2008.03.019 BindingDB Entry DOI: 10.7270/Q2C53MR6
					More data for this Ligand-Target Pair