BDBM50376280 CHEMBL259600

SMILES: CCCc1ccc(cc1)C(=O)Nc1cnc2ccccc2c1

InChI Key: InChIKey=ACMQNRGXOSFSMZ-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50376280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50376280 (CHEMBL259600) Show SMILES CCCc1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C19H18N2O/c1-2-5-14-8-10-15(11-9-14)19(22)21-17-12-16-6-3-4-7-18(16)20-13-17/h3-4,6-13H,2,5H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]RTX from human TRPV1 receptor expressed in HEK293 cells				Bioorg Med Chem Lett 18: 2730-4 (2008) Article DOI: 10.1016/j.bmcl.2008.02.075 BindingDB Entry DOI: 10.7270/Q27H1KF6
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50376280 (CHEMBL259600) Show SMILES CCCc1ccc(cc1)C(=O)Nc1cnc2ccccc2c1 Show InChI InChI=1S/C19H18N2O/c1-2-5-14-8-10-15(11-9-14)19(22)21-17-12-16-6-3-4-7-18(16)20-13-17/h3-4,6-13H,2,5H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Activity at human TRPV1 in HEK cells assessed by measuring capsaicin-induced calcium level by FLIPR technology				Bioorg Med Chem Lett 18: 2730-4 (2008) Article DOI: 10.1016/j.bmcl.2008.02.075 BindingDB Entry DOI: 10.7270/Q27H1KF6
					More data for this Ligand-Target Pair