null

SMILES: CC(C)(C)CN(Cc1ccccc1)c1ccnc(n1)C#N

InChI Key: InChIKey=OBQRXUXIAHCBPH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50376506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Homo sapiens (Human))	BDBM50376506 (CHEMBL261125) Show SMILES CC(C)(C)CN(Cc1ccccc1)c1ccnc(n1)C#N Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin K by fluorescence assay				Bioorg Med Chem Lett 18: 2599-603 (2008) Article DOI: 10.1016/j.bmcl.2008.03.036 BindingDB Entry DOI: 10.7270/Q2HT2Q6P
					More data for this Ligand-Target Pair
Cathepsin S (Homo sapiens (Human))	BDBM50376506 (CHEMBL261125) Show SMILES CC(C)(C)CN(Cc1ccccc1)c1ccnc(n1)C#N Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin S by fluorescence assay				Bioorg Med Chem Lett 18: 2599-603 (2008) Article DOI: 10.1016/j.bmcl.2008.03.036 BindingDB Entry DOI: 10.7270/Q2HT2Q6P
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50376506 (CHEMBL261125) Show SMILES CC(C)(C)CN(Cc1ccccc1)c1ccnc(n1)C#N Show InChI InChI=1S/C17H20N4/c1-17(2,3)13-21(12-14-7-5-4-6-8-14)16-9-10-19-15(11-18)20-16/h4-10H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for BioMedical Research Curated by ChEMBL					Assay Description Inhibition of human recombinant cathepsin L by fluorescence assay				Bioorg Med Chem Lett 18: 2599-603 (2008) Article DOI: 10.1016/j.bmcl.2008.03.036 BindingDB Entry DOI: 10.7270/Q2HT2Q6P
					More data for this Ligand-Target Pair