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SMILES: OC(=O)COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(cc1)C(F)(F)C(O)=O

InChI Key: InChIKey=GHBROPCSLNANSG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50376603   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM50376603
PNG
(CHEMBL259284)
Show SMILES OC(=O)COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)-c1csnn1)Cc1ccc(cc1)C(F)(F)C(O)=O
Show InChI InChI=1S/C26H21F2N3O7S2/c27-26(28,25(34)35)20-7-3-18(4-8-20)14-31(13-17-1-5-19(6-2-17)23-16-39-30-29-23)40(36,37)22-11-9-21(10-12-22)38-15-24(32)33/h1-12,16H,13-15H2,(H,32,33)(H,34,35)
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Article
PubMed
n/an/a 1.77E+4n/an/an/an/an/an/a



Affymax, Inc.

Curated by ChEMBL


Assay Description
Inhibition of PTP1B

Bioorg Med Chem Lett 18: 2719-24 (2008)


Article DOI: 10.1016/j.bmcl.2008.03.007
BindingDB Entry DOI: 10.7270/Q23J3DTX
More data for this
Ligand-Target Pair