BDBM50378160 CHEMBL4161684

SMILES: CCOC(=O)c1noc2c1C(=O)c1ncccc1C2=O

InChI Key: InChIKey=STGXNSQQPDARPC-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50378160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50378160 (CHEMBL4161684) Show SMILES CCOC(=O)c1noc2c1C(=O)c1ncccc1C2=O Show InChI InChI=1S/C13H8N2O5/c1-2-19-13(18)9-7-11(17)8-6(4-3-5-14-8)10(16)12(7)20-15-9/h3-5H,2H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of human TDP2 expressed in TDP2 deficient chicken DT40 whole cell extracts using TY19 DNA as substrate after 15 mins by by PAGE analysis				Eur J Med Chem 151: 777-796 (2018) Article DOI: 10.1016/j.ejmech.2018.04.024 BindingDB Entry DOI: 10.7270/Q20R9RZ8
					More data for this Ligand-Target Pair
Tyrosyl-DNA phosphodiesterase 2 (Homo sapiens (Human))	BDBM50378160 (CHEMBL4161684) Show SMILES CCOC(=O)c1noc2c1C(=O)c1ncccc1C2=O Show InChI InChI=1S/C13H8N2O5/c1-2-19-13(18)9-7-11(17)8-6(4-3-5-14-8)10(16)12(7)20-15-9/h3-5H,2H2,1H3	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sun Yat-sen University Curated by ChEMBL					Assay Description Inhibition of recombinant human TDP2 using TY18 (alpha-[32P]-cordycepin-3'-labeled) as substrate after 15 mins by PAGE analysis				Eur J Med Chem 151: 777-796 (2018) Article DOI: 10.1016/j.ejmech.2018.04.024 BindingDB Entry DOI: 10.7270/Q20R9RZ8
					More data for this Ligand-Target Pair