BDBM50381051 CHEMBL2017359

SMILES: NC(=O)c1cccc2c3sccc3c(Nc3ccccc3Cl)nc12

InChI Key: InChIKey=QBBDBUVPJDYPLQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50381051 (CHEMBL2017359) Show SMILES NC(=O)c1cccc2c3sccc3c(Nc3ccccc3Cl)nc12 Show InChI InChI=1S/C18H12ClN3OS/c19-13-6-1-2-7-14(13)21-18-12-8-9-24-16(12)10-4-3-5-11(17(20)23)15(10)22-18/h1-9H,(H2,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate and 30 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50381051 (CHEMBL2017359) Show SMILES NC(=O)c1cccc2c3sccc3c(Nc3ccccc3Cl)nc12 Show InChI InChI=1S/C18H12ClN3OS/c19-13-6-1-2-7-14(13)21-18-12-8-9-24-16(12)10-4-3-5-11(17(20)23)15(10)22-18/h1-9H,(H2,20,23)(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate and 5 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair