BDBM50381065 CHEMBL2017335

SMILES: C1CN(CCO1)c1nc2c(cccc2c2sccc12)-c1nnc[nH]1

InChI Key: InChIKey=KLSMNUWOPFTNED-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50381065 (CHEMBL2017335) Show SMILES C1CN(CCO1)c1nc2c(cccc2c2sccc12)-c1nnc[nH]1 Show InChI InChI=1S/C17H15N5OS/c1-2-11-14(12(3-1)16-18-10-19-21-16)20-17(13-4-9-24-15(11)13)22-5-7-23-8-6-22/h1-4,9-10H,5-8H2,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate and 30 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50381065 (CHEMBL2017335) Show SMILES C1CN(CCO1)c1nc2c(cccc2c2sccc12)-c1nnc[nH]1 Show InChI InChI=1S/C17H15N5OS/c1-2-11-14(12(3-1)16-18-10-19-21-16)20-17(13-4-9-24-15(11)13)22-5-7-23-8-6-22/h1-4,9-10H,5-8H2,(H,18,19,21)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate and 5 uM ATP by radiometric assay				Bioorg Med Chem Lett 22: 3327-31 (2012) Article DOI: 10.1016/j.bmcl.2012.02.099 BindingDB Entry DOI: 10.7270/Q2057GZB
					More data for this Ligand-Target Pair