BDBM50381175 CHEMBL2018384

SMILES: CCC[C@H](O)[C@H](CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)OC(C)(C)C)C(F)(F)F

InChI Key: InChIKey=DNHMKZCXTMRBSW-DQEYMECFSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381175   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50381175 (CHEMBL2018384) Show SMILES CCC[C@H](O)[C@H](CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)OC(C)(C)C)C(F)(F)F |r| Show InChI InChI=1S/C30H41F3N4O5/c1-7-8-25(38)24(16-34-15-20-10-9-18(2)13-19(20)3)36-26(39)17-35-27(40)22-14-21(30(31,32)33)11-12-23(22)37-28(41)42-29(4,5)6/h9-14,24-25,34,38H,7-8,15-17H2,1-6H3,(H,35,40)(H,36,39)(H,37,41)/t24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125-I]MCP1 from CCR2 on human PBMC				Bioorg Med Chem Lett 22: 3311-6 (2012) Article DOI: 10.1016/j.bmcl.2012.03.007 BindingDB Entry DOI: 10.7270/Q2PN96MB
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50381175 (CHEMBL2018384) Show SMILES CCC[C@H](O)[C@H](CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(ccc1NC(=O)OC(C)(C)C)C(F)(F)F |r| Show InChI InChI=1S/C30H41F3N4O5/c1-7-8-25(38)24(16-34-15-20-10-9-18(2)13-19(20)3)36-26(39)17-35-27(40)22-14-21(30(31,32)33)11-12-23(22)37-28(41)42-29(4,5)6/h9-14,24-25,34,38H,7-8,15-17H2,1-6H3,(H,35,40)(H,36,39)(H,37,41)/t24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Antagonist activity at CCR2 in human PBMC assessed as inhibition of MCP1-induced chemotaxis				Bioorg Med Chem Lett 22: 3311-6 (2012) Article DOI: 10.1016/j.bmcl.2012.03.007 BindingDB Entry DOI: 10.7270/Q2PN96MB
					More data for this Ligand-Target Pair