null

SMILES: Cc1noc2c(Cc3ccc(cc3)[N+]([O-])=O)nn(Cc3nnc(Nc4ccccc4)s3)c(=O)c12

InChI Key: InChIKey=RHRCRBLQCAWGCP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50381246 (CHEMBL2018567) Show SMILES Cc1noc2c(Cc3ccc(cc3)[N+]([O-])=O)nn(Cc3nnc(Nc4ccccc4)s3)c(=O)c12 Show InChI InChI=1S/C22H17N7O4S/c1-13-19-20(33-27-13)17(11-14-7-9-16(10-8-14)29(31)32)26-28(21(19)30)12-18-24-25-22(34-18)23-15-5-3-2-4-6-15/h2-10H,11-12H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Hacettepe Curated by ChEMBL					Assay Description Inhibition of human recombinant COX2 by fluorescence assay				Bioorg Med Chem 20: 2912-22 (2012) Article DOI: 10.1016/j.bmc.2012.03.021 BindingDB Entry DOI: 10.7270/Q2F76DKX
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM50381246 (CHEMBL2018567) Show SMILES Cc1noc2c(Cc3ccc(cc3)[N+]([O-])=O)nn(Cc3nnc(Nc4ccccc4)s3)c(=O)c12 Show InChI InChI=1S/C22H17N7O4S/c1-13-19-20(33-27-13)17(11-14-7-9-16(10-8-14)29(31)32)26-28(21(19)30)12-18-24-25-22(34-18)23-15-5-3-2-4-6-15/h2-10H,11-12H2,1H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Hacettepe Curated by ChEMBL					Assay Description Inhibition of ovine COX1 by fluorescence assay				Bioorg Med Chem 20: 2912-22 (2012) Article DOI: 10.1016/j.bmc.2012.03.021 BindingDB Entry DOI: 10.7270/Q2F76DKX
					More data for this Ligand-Target Pair