BDBM50381345 CHEMBL2016706

SMILES: CC(C)C(=O)N1CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(Cl)cc3)ccc2n1

InChI Key: InChIKey=RTXBYXZOKLASPV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50381345 (CHEMBL2016706) Show SMILES CC(C)C(=O)N1CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C25H28ClN5O3/c1-16(2)24(33)30-10-12-31(13-11-30)25-27-17(3)21-14-19(6-9-22(21)29-25)28-23(32)15-34-20-7-4-18(26)5-8-20/h4-9,14,16H,10-13,15H2,1-3H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH peptide mediated response measuring [3H]inositol phosphate...				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50381345 (CHEMBL2016706) Show SMILES CC(C)C(=O)N1CCN(CC1)c1nc(C)c2cc(NC(=O)COc3ccc(Cl)cc3)ccc2n1 Show InChI InChI=1S/C25H28ClN5O3/c1-16(2)24(33)30-10-12-31(13-11-30)25-27-17(3)21-14-19(6-9-22(21)29-25)28-23(32)15-34-20-7-4-18(26)5-8-20/h4-9,14,16H,10-13,15H2,1-3H3,(H,28,32)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assay				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair