null

SMILES: Cc1nc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(O)(CC1)c1ccc(F)cn1

InChI Key: InChIKey=LJLZIZYPEHICQG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381369   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381369 (CHEMBL2016786) Show SMILES Cc1nc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(O)(CC1)c1ccc(F)cn1 Show InChI InChI=1S/C28H25F4N5O4/c1-17-22-14-19(35-25(38)16-40-20-4-6-21(7-5-20)41-28(30,31)32)3-8-23(22)36-26(34-17)37-12-10-27(39,11-13-37)24-9-2-18(29)15-33-24/h2-9,14-15,39H,10-13,16H2,1H3,(H,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	213	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by SPA binding assay				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381369 (CHEMBL2016786) Show SMILES Cc1nc(nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12)N1CCC(O)(CC1)c1ccc(F)cn1 Show InChI InChI=1S/C28H25F4N5O4/c1-17-22-14-19(35-25(38)16-40-20-4-6-21(7-5-20)41-28(30,31)32)3-8-23(22)36-26(34-17)37-12-10-27(39,11-13-37)24-9-2-18(29)15-33-24/h2-9,14-15,39H,10-13,16H2,1H3,(H,35,38)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH peptide mediated response measuring [3H]inositol phosphate...				Bioorg Med Chem Lett 22: 3157-62 (2012) Article DOI: 10.1016/j.bmcl.2012.03.050 BindingDB Entry DOI: 10.7270/Q2D79CFJ
					More data for this Ligand-Target Pair