BDBM50381534 CHEMBL2017765

SMILES: CN(C)S(=O)(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1

InChI Key: InChIKey=IPKAHEIDQLFAOX-IZZDOVSWSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50381534   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381534 (CHEMBL2017765) Show SMILES CN(C)S(=O)(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C26H29F3N6O4S/c1-17-22-16-20(31-24(36)11-6-18-4-8-21(9-5-18)39-26(27,28)29)7-10-23(22)32-25(30-17)35-14-12-19(13-15-35)33-40(37,38)34(2)3/h4-11,16,19,33H,12-15H2,1-3H3,(H,31,36)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50381534 (CHEMBL2017765) Show SMILES CN(C)S(=O)(=O)NC1CCN(CC1)c1nc(C)c2cc(NC(=O)\C=C\c3ccc(OC(F)(F)F)cc3)ccc2n1 Show InChI InChI=1S/C26H29F3N6O4S/c1-17-22-16-20(31-24(36)11-6-18-4-8-21(9-5-18)39-26(27,28)29)7-10-23(22)32-25(30-17)35-14-12-19(13-15-35)33-40(37,38)34(2)3/h4-11,16,19,33H,12-15H2,1-3H3,(H,31,36)/b11-6+	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Ltd Curated by ChEMBL					Assay Description Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assay				Bioorg Med Chem Lett 22: 3163-7 (2012) Article DOI: 10.1016/j.bmcl.2012.03.049 BindingDB Entry DOI: 10.7270/Q20Z7485
					More data for this Ligand-Target Pair