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BDBM50381555 CHEMBL2018097

SMILES: OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2cc3ccccc3s2)c1

InChI Key: InChIKey=BDTYVRWUCYRNFY-RQXATKFSSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50381555   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium/glucose cotransporter 2


(Homo sapiens (Human))		BDBM50381555
PNG
(CHEMBL2018097)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H](O)[C@@H]1O)c1ccc(Cl)c(Cc2cc3ccccc3s2)c1 |r|
Show InChI InChI=1S/C21H21ClO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1
PDB

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.70n/an/an/an/an/an/a



Astellas Pharma Inc.

Curated by ChEMBL


Assay Description
Inhibition of human SGLT2 expressed in CHO cells assessed as [14C]AMG accumulation after 2 hrs by scintillation counting

Bioorg Med Chem 20: 3263-79 (2012)


Article DOI: 10.1016/j.bmc.2012.03.051
BindingDB Entry DOI: 10.7270/Q2W66MSS
More data for this
Ligand-Target Pair