BDBM50382295 CHEMBL2024507

SMILES: CC(=O)N[C@H]1CC[C@H](CCN2CCC(Cc3cccc(c3)C(F)(F)F)CC2)CC1

InChI Key: InChIKey=ACKBCTLAXFJWPZ-LBZQVFOQSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50382295 (CHEMBL2024507) Show SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCC(Cc3cccc(c3)C(F)(F)F)CC2)CC1 |r,wU:4.3,wD:7.7,(4.59,-14.97,;5.92,-14.2,;5.88,-12.66,;7.25,-14.97,;8.59,-14.19,;8.59,-12.65,;9.92,-11.88,;11.24,-12.65,;12.58,-11.89,;13.91,-12.66,;15.25,-11.9,;16.57,-12.68,;17.91,-11.92,;17.92,-10.38,;19.26,-9.61,;20.59,-10.39,;21.92,-9.63,;23.25,-10.41,;23.25,-11.94,;21.92,-12.71,;20.58,-11.93,;21.92,-14.25,;20.58,-15.02,;23.25,-15.02,;21.93,-15.8,;16.59,-9.6,;15.24,-10.36,;11.24,-14.19,;9.92,-14.96,)| Show InChI InChI=1S/C23H33F3N2O/c1-17(29)27-22-7-5-18(6-8-22)9-12-28-13-10-19(11-14-28)15-20-3-2-4-21(16-20)23(24,25)26/h2-4,16,18-19,22H,5-15H2,1H3,(H,27,29)/t18-,22-	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat striatal membranes				Bioorg Med Chem Lett 22: 3437-40 (2012) Article DOI: 10.1016/j.bmcl.2012.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1MZN
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50382295 (CHEMBL2024507) Show SMILES CC(=O)N[C@H]1CC[C@H](CCN2CCC(Cc3cccc(c3)C(F)(F)F)CC2)CC1 |r,wU:4.3,wD:7.7,(4.59,-14.97,;5.92,-14.2,;5.88,-12.66,;7.25,-14.97,;8.59,-14.19,;8.59,-12.65,;9.92,-11.88,;11.24,-12.65,;12.58,-11.89,;13.91,-12.66,;15.25,-11.9,;16.57,-12.68,;17.91,-11.92,;17.92,-10.38,;19.26,-9.61,;20.59,-10.39,;21.92,-9.63,;23.25,-10.41,;23.25,-11.94,;21.92,-12.71,;20.58,-11.93,;21.92,-14.25,;20.58,-15.02,;23.25,-15.02,;21.93,-15.8,;16.59,-9.6,;15.24,-10.36,;11.24,-14.19,;9.92,-14.96,)| Show InChI InChI=1S/C23H33F3N2O/c1-17(29)27-22-7-5-18(6-8-22)9-12-28-13-10-19(11-14-28)15-20-3-2-4-21(16-20)23(24,25)26/h2-4,16,18-19,22H,5-15H2,1H3,(H,27,29)/t18-,22-	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat recombinant dopamine D3 receptor expressed in Sf9 cells				Bioorg Med Chem Lett 22: 3437-40 (2012) Article DOI: 10.1016/j.bmcl.2012.03.104 BindingDB Entry DOI: 10.7270/Q2ZW1MZN
					More data for this Ligand-Target Pair