BDBM50382760 CHEMBL2024590

SMILES: Cc1cc(CC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)c2ccc(CN3CCCCC3)cn2)cc2cn[nH]c12

InChI Key: InChIKey=VCAWQPVISZKOIS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50382760   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50382760 (CHEMBL2024590) Show SMILES Cc1cc(CC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)c2ccc(CN3CCCCC3)cn2)cc2cn[nH]c12 Show InChI InChI=1S/C36H43N7O2/c1-25-17-27(19-30-22-38-40-35(25)30)18-29(32-10-9-26(21-37-32)23-41-13-5-2-6-14-41)20-34(44)42-15-11-31(12-16-42)43-24-28-7-3-4-8-33(28)39-36(43)45/h3-4,7-10,17,19,21-22,29,31H,2,5-6,11-16,18,20,23-24H2,1H3,(H,38,40)(H,39,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Antagonist activity at CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production				Bioorg Med Chem Lett 22: 2917-21 (2012) Article DOI: 10.1016/j.bmcl.2012.02.065 BindingDB Entry DOI: 10.7270/Q2FQ9XN0
					More data for this Ligand-Target Pair
Calcitonin gene-related peptide type 1 receptor (Homo sapiens (Human))	BDBM50382760 (CHEMBL2024590) Show SMILES Cc1cc(CC(CC(=O)N2CCC(CC2)N2Cc3ccccc3NC2=O)c2ccc(CN3CCCCC3)cn2)cc2cn[nH]c12 Show InChI InChI=1S/C36H43N7O2/c1-25-17-27(19-30-22-38-40-35(25)30)18-29(32-10-9-26(21-37-32)23-41-13-5-2-6-14-41)20-34(44)42-15-11-31(12-16-42)43-24-28-7-3-4-8-33(28)39-36(43)45/h3-4,7-10,17,19,21-22,29,31H,2,5-6,11-16,18,20,23-24H2,1H3,(H,38,40)(H,39,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research& Development Curated by ChEMBL					Assay Description Displacement of [I125]CGRP from CGRP receptor in human SK-N-MC cell membrane after 2 hrs by gamma or scintillation counting				Bioorg Med Chem Lett 22: 2917-21 (2012) Article DOI: 10.1016/j.bmcl.2012.02.065 BindingDB Entry DOI: 10.7270/Q2FQ9XN0
					More data for this Ligand-Target Pair