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SMILES: Cc1nc2cc(ccc2o1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1

InChI Key: InChIKey=UWKLENCDKKIQFX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383443   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Homo sapiens (Human))		BDBM50383443
PNG
(CHEMBL2031603)
Show SMILES Cc1nc2cc(ccc2o1)-c1nnc(s1)N1CCC(CC1)N1CCCCC1
Show InChI InChI=1S/C20H25N5OS/c1-14-21-17-13-15(5-6-18(17)26-14)19-22-23-20(27-19)25-11-7-16(8-12-25)24-9-3-2-4-10-24/h5-6,13,16H,2-4,7-12H2,1H3
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 24.5n/an/an/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]N-alpha-methylhistamine from recombinant human histamine H3 receptor expressed in HEK cell membranes after 30 mins by scintillati...

Bioorg Med Chem Lett 22: 3354-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.02.076
BindingDB Entry DOI: 10.7270/Q2DN462S
More data for this
Ligand-Target Pair