BDBM50383940 CHEMBL2031973

SMILES: COc1c(cc(cc1C(C)(C)C)C(=O)N1CCN([C@@H](C)C1)C(=O)CCCCC(c1ccc(F)cc1)c1ccc(F)cc1)C(C)(C)C

InChI Key: InChIKey=HTTLIQFTUASLKJ-SANMLTNESA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383940   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50383940 (CHEMBL2031973) Show SMILES COc1c(cc(cc1C(C)(C)C)C(=O)N1CCN([C@@H](C)C1)C(=O)CCCCC(c1ccc(F)cc1)c1ccc(F)cc1)C(C)(C)C |r| Show InChI InChI=1S/C39H50F2N2O3/c1-26-25-42(37(45)29-23-33(38(2,3)4)36(46-8)34(24-29)39(5,6)7)21-22-43(26)35(44)12-10-9-11-32(27-13-17-30(40)18-14-27)28-15-19-31(41)20-16-28/h13-20,23-24,26,32H,9-12,21-22,25H2,1-8H3/t26-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Zalicus Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of human Erg expressed in HEK293 cells by whole cell patch clamp analysis				Bioorg Med Chem Lett 22: 4153-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.054 BindingDB Entry DOI: 10.7270/Q2PZ59TV
					More data for this Ligand-Target Pair