BDBM50383947 CHEMBL2031982

SMILES: Fc1ccc(cc1)C(CCCCCN1CCC(CNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C1)c1ccc(F)cc1

InChI Key: InChIKey=RYLXNIBUJUTFDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383947   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50383947 (CHEMBL2031982) Show SMILES Fc1ccc(cc1)C(CCCCCN1CCC(CNC(=O)c2cc(cc(c2)C(F)(F)F)C(F)(F)F)C1)c1ccc(F)cc1 Show InChI InChI=1S/C32H32F8N2O/c33-27-9-5-22(6-10-27)29(23-7-11-28(34)12-8-23)4-2-1-3-14-42-15-13-21(20-42)19-41-30(43)24-16-25(31(35,36)37)18-26(17-24)32(38,39)40/h5-12,16-18,21,29H,1-4,13-15,19-20H2,(H,41,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Zalicus Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of human Erg expressed in HEK293 cells by whole cell patch clamp analysis				Bioorg Med Chem Lett 22: 4153-8 (2012) Article DOI: 10.1016/j.bmcl.2012.04.054 BindingDB Entry DOI: 10.7270/Q2PZ59TV
					More data for this Ligand-Target Pair