BDBM50384718 CHEMBL2037205

SMILES: CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(o1)C(C)=C1C(=O)Nc2ccc(Cl)cc12

InChI Key: InChIKey=VJWOOBJEGKYLAB-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50384718   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384718 (CHEMBL2037205) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(o1)C(C)=C1C(=O)Nc2ccc(Cl)cc12 Show InChI InChI=1S/C27H26ClN3O3/c1-17(25-21-16-20(28)7-8-22(21)29-26(25)32)23-9-10-24(34-23)18-5-3-6-19(15-18)27(33)31-12-4-11-30(2)13-14-31/h3,5-10,15-16H,4,11-14H2,1-2H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50384718 (CHEMBL2037205) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(o1)C(C)=C1C(=O)Nc2ccc(Cl)cc12 Show InChI InChI=1S/C27H26ClN3O3/c1-17(25-21-16-20(28)7-8-22(21)29-26(25)32)23-9-10-24(34-23)18-5-3-6-19(15-18)27(33)31-12-4-11-30(2)13-14-31/h3,5-10,15-16H,4,11-14H2,1-2H3,(H,29,32)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair