BDBM50384973 CHEMBL2035057
SMILES: Cc1nc(sc1C(CC1CC1)Sc1ccc(OCC(O)=O)c(C)c1)-c1ccc(cc1)C(F)(F)F
InChI Key: InChIKey=MQWQMHPKGLTROT-UHFFFAOYSA-N
Data: 3 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Peroxisome proliferator-activated receptor delta (Homo sapiens (Human)) | BDBM50384973 (CHEMBL2035057) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Transactivation activity at human PPARdelta expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assay | Eur J Med Chem 53: 190-202 (2012) Article DOI: 10.1016/j.ejmech.2012.03.055 BindingDB Entry DOI: 10.7270/Q2JW8FX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor (Homo sapiens (Human)) | BDBM50384973 (CHEMBL2035057) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Transactivation activity at human PPARgamma expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assay | Eur J Med Chem 53: 190-202 (2012) Article DOI: 10.1016/j.ejmech.2012.03.055 BindingDB Entry DOI: 10.7270/Q2JW8FX2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human)) | BDBM50384973 (CHEMBL2035057) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 861 | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Transactivation activity at human PPARalpha expressed in african green monkey CV1 cells after 24 hrs by luciferase reporter gene assay | Eur J Med Chem 53: 190-202 (2012) Article DOI: 10.1016/j.ejmech.2012.03.055 BindingDB Entry DOI: 10.7270/Q2JW8FX2 | |||||||||||
More data for this Ligand-Target Pair |