BindingDB logo
myBDB logout

null

SMILES: Clc1cccc(CNC(=O)[C@H]2CN(CC3CC3)C[C@H]2C(=O)NC2CCN(Cc3ccccc3)C2)c1

InChI Key: InChIKey=ACNAIGITXKGCML-XBCLTQTASA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50385163   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanocortin receptor 4


(Homo sapiens (Human))		BDBM50385163
PNG
(CHEMBL2035943)
Show SMILES Clc1cccc(CNC(=O)[C@H]2CN(CC3CC3)C[C@H]2C(=O)NC2CCN(Cc3ccccc3)C2)c1 |r|
Show InChI InChI=1S/C28H35ClN4O2/c29-23-8-4-7-22(13-23)14-30-27(34)25-18-33(16-21-9-10-21)19-26(25)28(35)31-24-11-12-32(17-24)15-20-5-2-1-3-6-20/h1-8,13,21,24-26H,9-12,14-19H2,(H,30,34)(H,31,35)/t24?,25-,26+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
 400n/an/an/an/an/an/an/an/a



Neurocrine Biosciences

Curated by ChEMBL


Assay Description
Displacement of [125I]NDPMSH from human MC4 receptor expressed in HEK293 cells after 2 hrs by liquid scintillation counting

Bioorg Med Chem 20: 3565-74 (2012)


Article DOI: 10.1016/j.bmc.2012.04.001
BindingDB Entry DOI: 10.7270/Q24M95K5
More data for this
Ligand-Target Pair